CK-869 是肌动蛋白相关蛋白 2/3 复合体 (ARP2/3) 的抑制剂,其 IC50 值为 7 μM。 Product description CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM. Product Application CK-869 has been used as an Arp2/3 complex inhibitor: to treat cultured mammalian cells and study its in vitro and in vivo effects on microtubule assembly to induce membrane blebbing in HT1080 fibrosarcoma cells to treat KDM3A-null cells and study the relation between actin dynamics and ciliogenesis
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
CK869
Dangerous GoodsCAS number:388592-44-7 molecular formula:C17H16BrNO3S
overview
compound introduction
Specs
| Chinese alias | 2-(3-溴苯基)-3-(2,4-二甲氧基苯基)-4-噻唑烷酮 | ||
| English alias | HMS623C22 | CCG-33400 | 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone | D80737 | BS-17180 | EX-A2784 | SR-01000553731-1 | CK 869 | CK 869; CK869; CK-0157869; CK 0157869; CK0157869 | 2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4- | ||
| CAS number | 388592-44-7 | molecular formula | C17H16BrNO3S |
| molecular weight | 394.28 g/mol | Exact mass | 10mM in DMSO |
| PSA | 64.099 Ų | logp | 4.000 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS09
Signal word:
Warning
Hazard Statement:
H400: 对水生生物有剧毒
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P391: 收集溢出物
WGK Germany:
3
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS





