CAS number：878385-84-3 molecular formula：C18H22F2N4O5S2
AZD-5069 是有效的 CXCR2 chemokine 受体拮抗剂，用于癌症的研究。 Targets CXCR2 In vitro AZD5069 is a slowly reversible antagonist of CXCR2 with effects of time and temperature evident on the pharmacology and binding kinetics. In vivo In preclinical models, airway neutrophil recruitment in response to inflammatory challenge is abrogated by selective targeting of CXCR2 using AZD5069.
| Chinese alias | - | ||
| English alias | C18H22F2N4O5S2 | N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-4-pyrimidinyl]-1-azetidinesulfonamide | HY-19855 | AKOS037649275 | N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)az | ||
| CAS number | 878385-84-3 | molecular formula | C18H22F2N4O5S2 |
| molecular weight | 476.52 g/mol | Exact mass | - |
| PSA | 159.000 Ų | logp | 1.500 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
