CAS number：1227634-69-6 molecular formula：C24H25N7
GNF351 是一种 aryl hydrocarbon receptor (AHR) 的有效拮抗剂。GNF351 可直接与AHR配体结合袋相互作用，并与特征明确的光亲和性AHR配体竞争结合AHR，对应的IC50值为62 nM。 Information GNF351 GNF351 is a potent antagonist of aryl hydrocarbon receptor (AHR) . GNF351 interacts directly with the AHR ligand binding pocket and competes with a well-characterized photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM. Targets AhR (Cell-free assay) 62 nM
| Chinese alias | - | ||
| English alias | N-[2-(1H-indol-3-yl)ethyl]-2-(5-methylpyridin-3-yl)-9-propan-2-ylpurin-6-amine | N-(2-(1H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methylpyridin-3-yl)-9H-purin-6-amine | ||
| CAS number | 1227634-69-6 | molecular formula | C24H25N7 |
| molecular weight | 411.5 g/mol | Exact mass | ≥98% |
| PSA | 84.300 Ų | logp | 4.199 |
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