LX-4211是SGLT1/2抑制剂,是抗糖尿病剂。 Sotagliflozin (LX4211, LP-802034)是一种双重SGLT1/SGLT2抑制剂,IC50分别为 36 nM 和 1.8 nM。 LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents.
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LX-4211
Dangerous GoodsCAS number:1018899-04-1 molecular formula:C21H25ClO5S
overview
compound introduction
Specs
| Chinese alias | 索格列净 | ||
| English alias | A852129 | Sotagliflozin (LX4211) | Sotagliflozin (LX-4211) | 1018899-04-1 | Tox21_501139 | UNII-6B4ZBS263Y | (2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-tetrahydro-6-(methylthio)-2H-pyran-3,4,5-triol;LX4211 | DTXSID20144314 | SOTAGLIFLOZIN [MI] | ||
| CAS number | 1018899-04-1 | molecular formula | C21H25ClO5S |
| molecular weight | 424.94 g/mol | Exact mass | - |
| PSA | 104.000 Ų | logp | 3.2 |
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physicochemical properties
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Safety information
pictogram:
GHS08
Signal word:
Warning
Hazard Statement:
H351: 怀疑引起遗传缺陷 H373: 通过长时间或反复暴露对器官造成损害 H413: 可能对水生生物造成长期的有害影响
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。 P319: 如果你感到不适,请寻求医疗帮助。
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