CAS number：40045-50-9 molecular formula：C5H3N5O2S3
SU3327 是一种有效的，选择性的且具有底物竞争性的 JNK 抑制剂，IC50 为 0.7 μM。SU3327 还以 IC50 值为 239 nM 抑制 JNK 和 JIP 之间的蛋白相互作用。SU3327 对 p38α 和 Akt 激酶的活性较低。 Product description： SU3327 is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM. SU3327 also inhibits protein-protein interactions between JNK and JNK Interacting Protein (JIP) with an IC50 of 239 nM. SU3327 shows less active against p38α and Akt kinase.
| Chinese alias | 5-((5-硝基噻唑-2-基)硫基)-1,3,4-噻二唑-2-胺 | ||
| English alias | 5-(5-Nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine | AKOS040739250 | 1,3,4-Thiadiazol-2-amine, 5-((5-nitro-2-thiazolyl)thio)- | 5-[(5-Nitro-2-thiazolyl)thio]-1,3,4-thiadiazol-2-amine | 5-[(5-Nitro-2-thiazolyl)thio]-1,3,4thiadiazol-2-amine | compound 9 [ | ||
| CAS number | 40045-50-9 | molecular formula | C5H3N5O2S3 |
| molecular weight | 261.29 g/mol | Exact mass | - |
| PSA | 192.000 Ų | logp | 1.9 |
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