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IWP-3

CAS number:687561-60-0(DMSO)    molecular formula:C22H17FN4O2S3

overview

compound introduction

IWP-3 is an potent inhibitor of Wnt production with an IC 50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1γ3 and CK1ε only moderately and does not inhibit CK1α.

Specs

Chinese alias-
English alias-
CAS number687561-60-0(DMSO)molecular formulaC22H17FN4O2S3
molecular weight484.59 g/molExact mass10mM in DMSO
PSA-logp-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害
Statement of Preventive Measures:
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
WGK Germany:
3

Production methods and uses

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upstream information

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downstream information

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MSDS

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