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DIF-3

CAS number：113411-17-9(DMSO)    molecular formula：C13H17ClO4

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compound introduction

DIF-3 reduces the expression levels of cyclin D1 and c-Myc by facilitating their degradation via activation of GSK-3β. DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. DIF-3 exerts a strong antiproliferative effect on the human cervical cancer cell line HeLa by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression.

Specs

Chinese alias-
English alias-
CAS number113411-17-9(DMSO)molecular formulaC13H17ClO4
molecular weight272.72 g/molExact mass10mM in DMSO
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numbering system

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physicochemical properties

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Safety information

WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

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