Dinaciclib (SCH727965)

Dangerous Goods

CAS number：779353-01-4 molecular formula：C21H28N6O2

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Dinaciclib (SCH727965)是CDK抑制剂，对CDK2，CDK5，CDK1和CDK9的IC50分别为1 nM，1 nM，3 nM和4 nM。A novel and potent cyclin-dependent kinase inhibitor for Cdk2, Cdk5, Cdk1, and Cdk9 Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. A novel and potent cyclin-dependent kinase inhibitor for Cdk2, Cdk5, Cdk1, and Cdk9

Specs

Chinese alias	-
English alias	1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol \| NSC800091 \| NSC-800091 \| 4V8ECV0NBQ \| D09604 \| HY-10492 \| 2H-Pyran-2-one, tetrahydro-6-heptyl \| DINACICLIB [INN] \| SCH 727965 \| SW220016-1 \| 2-[(2S)-1-[
CAS number	779353-01-4	molecular formula	C21H28N6O2
molecular weight	396.49 g/mol	Exact mass	-
PSA	91.200 Å²	logp	1.9

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram：

GHS08 , GHS07

Signal word：

Danger

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H372: 通过长时间或反复暴露对器官造成损害 H340: 可能导致遗传缺陷

Statement of Preventive Measures：

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时，请勿进食、饮水或