2-[(1-Methylpropyl)dithio]-1H-imidazole

Dangerous Goods

CAS number：141400-58-0 molecular formula：C7H12N2S2

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

PX-12(IV-2)是可逆的硫氧还蛋白-1（Trx-1）抑制剂；抑制MCF-7 和HT-29 cells细胞生长的IC50值分别为1.9和2.9 μM。 PX 12 has been used as a thioredoxin 1 inhibitor prostate cancer cell lines to analyse its effect on cell viability. It has also been used as a hypoxia-inducible factor (HIF)-1α inhibitor to treat H2228 cells.

Specs

Chinese alias	2-[(1-甲基丙基)二硫代]-1H-咪唑
English alias	EX-A2436 \| PX12 \| PX-12 \| PX-12 compound \| BRD-A56592690-001-01-9 \| HMS3747E17 \| J-007491 \| NCGC00346876-01 \| S-BUTYL (2-IMIDAZOLYL) DISULFIDE \| 2-(sec-butyldisulfanyl)-1H-imidazole. \| D-Tyrosine, Vetec(TM) reagent grade, 99% \| Iv 2 Compound \| IV-2 compou
CAS number	141400-58-0	molecular formula	C7H12N2S2
molecular weight	188.31 g/mol	Exact mass	10mM in DMSO
PSA	79.300 Å²	logp	2.3

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移

WGK Germany：