SCH28080 是一种可逆的,K+ 竞争性的胃 H,K-ATPase 抑制剂,Ki 值 为 0.12 μM。SCH28080 在体内是有效的酸分泌抑制剂,具有抗溃疡作用。 Product description SCH28080 is a reversible, K+-competitive inhibitor of the gastric H,K-ATPase, with a Ki of 0.12 μM. SCH28080 is an effective inhibitor of acid secretion in vivo and with anti-gastric ulcer activity. Product Application SCH-28080 was used to treat zebrafish embryos to study the role of H+/K+-ATPase in establishment of left-right axis during development.
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SCH 28080
Dangerous GoodsCAS number:76081-98-6 molecular formula:C17H15N3O
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compound introduction
Specs
| Chinese alias | 2-甲基-8-(苯基甲氧基)咪唑并[1,2-a]吡啶-3-乙腈 | ||
| English alias | LP00439 | S28080 | Lopac-S-4443 | NCGC00015953-01 | NCGC00015953-03 | S 4443 | SCH28080 | Sch-28080 | FT-0641585 | SDCCGSBI-0050424.P002 | (8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-acetonitrile | (8-Benzyloxy-2-methylimidazo[1,2-a]pyridin-3-yl)ace | ||
| CAS number | 76081-98-6 | molecular formula | C17H15N3O |
| molecular weight | 277.33 g/mol | Exact mass | ≥98% |
| PSA | 50.300 Ų | logp | 3.300 |
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Safety information
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
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