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IWP 12

Dangerous Goods

CAS number:688353-45-9    molecular formula:C18H18N4O2S3

overview

compound introduction

IWP-12 是 porcupine (PORCN) 的有效抑制剂,并抑制细胞自主的 Wnt 信号,IC50为 15 nM。 Product Describtion: IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autono mous Wnt signaling with an IC50 of 15 nM.

Specs

Chinese aliasN-(6-甲基-2-苯并噻唑基)-2-[((3,4,6,7-四氢-3,6-二甲基-4-氧噻吩并[3,2-d]嘧啶-2-基)硫代]乙酰胺
English aliasIWP-12 | 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(5-methylbenzo[d]thiazol-2-yl)acetamide | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]acetamide
CAS number688353-45-9molecular formulaC18H18N4O2S3
molecular weight418.56 g/molExact mass≥98%(HPLC)
PSA154.000 Ųlogp3.700

numbering system

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physicochemical properties

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Safety information

WGK Germany:
3

Production methods and uses

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