compound introduction
TAO Kinase inhibitor 1 (compound 43) 是一种选择性的、ATP 竞争性的 thousand-and-one amino acid kinases (TAOK) 抑制剂，针对 TAOK1 和 TAOK2 的 IC50s 分别为 11 nM 和 15 nM。TAO Kinase inhibitor 1 延迟有丝分裂以及诱导有丝分裂细胞死亡。
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CP 43
Dangerous GoodsCAS number：850467-66-2 molecular formula：C25H24N2O2
overview
Specs
| Chinese alias | N-(2-氧-2-(((1,2,3,4-四氢萘-1-基)氨基)乙基)-[1,1'-联苯] -4-羧酰胺 | ||
| English alias | - | ||
| CAS number | 850467-66-2 | molecular formula | C25H24N2O2 |
| molecular weight | 384.47 g/mol | Exact mass | 10mM in DMSO |
| PSA | 58.200 Ų | logp | 4.400 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
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MSDS
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