application: AZD-7762 hydrochloride has been used: as a checkpoint kinase 1 and 2 (CHK1/2) inhibitor to study its effect on the efficiency of non-homologous end-joining (NHEJ) repair in breast cancer cell lines as a CHK1 inhibitor to serve as a positive control for replication stress in the assessment of fork restart events as a CHK1/2 inhibitor to study its effects on DNA lesions during mice zygote development
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AZD 7762 hydrochloride
Dangerous GoodsCAS number:1246094-78-9 molecular formula:C17H19FN4O2S•HCl
overview
compound introduction
Specs
| Chinese alias | 3-[(氨基羰基)氨基] -5-(3-氟苯基)-N-(3S)-3-哌啶基-2-噻吩羧酰胺盐酸盐 | ||
| English alias | MLS006010750 | HY-10992A | SCHEMBL19457662 | 5-(3-Fluoro-phenyl)-3-ureido-thiophene-2-carboxylic acid (S)-piperidin-3-ylamide hydrochloride | AZD-7762 hydrochloride, >=98% (HPLC) | AZD 7762 hydrochloride | SMR004701703 | BCP25387 | 3-(carbamoylamino)-5-(3 | ||
| CAS number | 1246094-78-9 | molecular formula | C17H19FN4O2S•HCl |
| molecular weight | 398.88 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 124.000 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS05 , GHS07
Signal word:
Danger
Hazard Statement:
H302: 吞食有害 H318: 造成严重的眼睛损伤
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽:请寻求医疗帮助。 P305+P354+P338: 如果进入眼睛:立即用水冲洗几分钟。取下隐形眼镜(如果有的话),并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。
WGK Germany:
3
Production methods and uses
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upstream information
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downstream information
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MSDS
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