PF-04971729(Ertμgliflozin)是钠离子依赖的葡萄糖协同转运蛋白2(SGLT2)抑制剂。 PF-04971729(Ertugliflozin) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2(SGLT2). Ertugliflozin (MK-8835, PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0.877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1.
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PF-04971729
Dangerous GoodsCAS number:1210344-57-2 molecular formula:C22H25ClO7
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-hydroxymethyl-6,8-dioxabicyclo(3.2.1)octane-2,3,4-triol | ERTUGLIFLOZIN COMPONENT OF SEGLUROMET | NCGC00163125-02 | AS-35204 | beta-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl | ||
| CAS number | 1210344-57-2 | molecular formula | C22H25ClO7 |
| molecular weight | 436.88 g/mol | Exact mass | - |
| PSA | 109.000 Ų | logp | 1.7 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS05
Signal word:
Danger
Hazard Statement:
H314: 造成严重的皮肤灼伤和眼睛损伤 H318: 造成严重的眼睛损伤
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P301+P330+P331: 如误吞咽:漱口。不要诱导呕吐。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P363: 再次使用之前,请清洗受污染的衣物。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P
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MSDS
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