CAS number：978-62-1 molecular formula：C15H8ClF6NO2
IMD-0354 (IKK2 Inhibitor V) 是一种选择性 IKKβ 抑制剂，抑制 NF-κB 活性。IMD0354 抑制 TNF-α 诱导的 NF-κB 转录活性，IC50 为 1.2 μM。 application： IMD-0354 has been used to study the effect of NF-κB (nuclear factor) inhibition on differentially expressed in chondrocytes 2. It has also been used to study the role of NF-κB signaling in tumor necrosis factor-induced certain transcription factors expression using human primary fibroblasts.
| Chinese alias | IKK-2 抑制剂 V | ||
| English alias | AKOS017344958 | NCGC00165811-02 | NSC800773 | NSC-800773 | SMR004702969 | HMS3269F13 | HMS3677J21 | IKK-2-inhibitor-V | HMS3651D21 | N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide | s2864 | SB19541 | SCHEMBL129165 | BCP0726000026 | BCP2235 | ||
| CAS number | 978-62-1 | molecular formula | C15H8ClF6NO2 |
| molecular weight | 383.67 g/mol | Exact mass | ≥99% |
| PSA | 49.300 Ų | logp | 6.200 |
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