CAS number：610798-31-7 molecular formula：C22H21N3O4
cotinib是一种有效的，特异性EGFR抑制剂，IC50为5 nM，包括EGFR， EGFR(L858R)， EGFR(L861Q)， EGFR(T790M)和EGFR(T790M， L858R)。 Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).
| Chinese alias | 埃克替尼 | ||
| English alias | N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine | Q15634085 | Q16868421 | SCHEMBL5843603 | DB11737 | NCGC00386224-06 | Conmana | EX-A306 | MFCD22124501 | 4-((3-ethynylphenyl)amino)-6,7-benzo | ||
| CAS number | 610798-31-7 | molecular formula | C22H21N3O4 |
| molecular weight | 391.42 g/mol | Exact mass | - |
| PSA | 74.700 Ų | logp | 3.1 |
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