compound introduction
ANA-12是有效，选择性的 TrkB 拮抗剂，对高亲和力和低亲和力位点的IC50 分别为45.6 nM和41.1 μM。 ANA-12 is an effective and selective TrkB antagonist with IC50 of 45.6 nM and 41.1 μM for high affinity and low affinity sites respectively.
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ANA-12
Dangerous GoodsCAS number：219766-25-3 molecular formula：C22H21N3O3S
overview
Specs
| Chinese alias | N- 2-(六氢-2-氧代-1H-氮杂卓-3-基)氨基羰基苯基-苯并b噻吩-2-甲酰胺 | ||
| English alias | AS-16798 | DTXSID501045818 | HY-12497 | A878840 | CHEBI:140465 | ANA12 | ANA-12 | N-{2-[(2-oxoazepan-3-yl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide | N-(2-(((Hexahydro-2-oxo-1H-azepin-3-yl)amino)carbonyl)phenyl)benzo(b)thiophene-2-carboxamide | SCH | ||
| CAS number | 219766-25-3 | molecular formula | C22H21N3O3S |
| molecular weight | 407.49 g/mol | Exact mass | 10mM in DMSO |
| PSA | 116.000 Ų | logp | 4.200 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
WGK Germany：
3
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MSDS
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