Tyrphostin AG 528

Dangerous Goods

CAS number：133550-49-9 molecular formula：C18H14N2O3

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Tyrphostin是EGFR蛋白酪氨酸激酶的有效抑制剂。 Tyrphostin AG-528 (Tyrphostin B66) 是一种蛋白酪氨酸激酶抑制剂，对表皮生长因子受体 (EGFR) 的 IC50 为 4.9 μM，对 ErbB2 的 IC50 为 2.1 μM。Tyrphostin AG-528 也是一种抗癌剂。 Tyrphostin is a potent inhibitor of EGFR protein tyrosine kinase. product description： Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC50s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for ErbB2. Tyrphostin AG 528 is also an anticancer agent.

Specs

Chinese alias	酪氨酸磷酸化抑制剂 AG 528
English alias	AC-35701 \| BCP24141 \| AG 528 \| BDBM4314 \| EX-A2364 \| SMR001230652 \| (2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile \| T3504 \| HMS2234E10 \| Tyrphostin AG 528 \| MLS002153157 \| AKOS030632031 \| D92708 \| MFCD01076474 \| N-(3'
CAS number	133550-49-9	molecular formula	C18H14N2O3
molecular weight	306.32 g/mol	Exact mass	≥98%
PSA	84.600 Å²	logp	2.600

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08

Signal word：

Warning

Hazard Statement：

H373: 通过长时间或反复暴露对器官造成损害 H371: 可能会损坏器官

Statement of Preventive Measures：

P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P308+P316: 如果暴露或担心：立即寻求紧急医疗救助。 P319: 如果你感到不适，请寻求医疗帮助。