compound introduction
ARN-509是竞争性雄激素受体抑制剂，IC50为16 nM，可作用于前列腺癌。 ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment.
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ARN-509
Dangerous GoodsCAS number：956104-40-8 molecular formula：C21H15F4N5O2S
overview
Specs
| Chinese alias | - | ||
| English alias | Uremide | Erleada (TN) | Z2037280438 | Erleada | HY-16060 | 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2-fluoro-N-methylbenzamide | APALUTAMIDE [MI] | SCHEMBL909297 | CCG-264760 | MFCD22380626 | NCG | ||
| CAS number | 956104-40-8 | molecular formula | C21H15F4N5O2S |
| molecular weight | 477.43 g/mol | Exact mass | - |
| PSA | 121.000 Ų | logp | 3 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS08 , GHS09 , GHS07
Signal word：
Danger
Hazard Statement：
H373: 通过长时间或反复暴露对器官造成损害 H302: 吞食有害 H410: 对水生生物有剧毒并具有长期持续影响 H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。 P319: 如果你感到不适，请寻求
Production methods and uses
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upstream information
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downstream information
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MSDS
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