Ospemifene 是一种非雌激素选择性雌激素受体 (estrogen receptor) 调节剂 (SERM),对雌激素受体 α (ERα) 和 ERβ 的 Kis值分别为 380 和 410 nM。Ospemifene 可用于阴道萎缩乳腺癌的研究。 Ospemifene is a non-hormonal selective estrogen receptor modulator (SERM), used for the treatment of dyspareunia.
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Ospemifene
Dangerous GoodsCAS number:128607-22-7 molecular formula:C24H23ClO2
overview
compound introduction
Specs
| Chinese alias | 奥培米芬 | ||
| English alias | J-005613 | Ophena | senshio | CCRIS 9205 | Q7107372 | A14261 | 2-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol | Fc-1271 | Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]- | OSPEMIFENE [ORANGE BOOK] | B0P231ILBK | MFCD00871890 | Osp | ||
| CAS number | 128607-22-7 | molecular formula | C24H23ClO2 |
| molecular weight | 378.9 g/mol | Exact mass | - |
| PSA | 29.500 Ų | logp | 6.5 |
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physicochemical properties
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Safety information
pictogram:
GHS09 , GHS05 , GHS07
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H411: 对水生生物有毒并具有长期持续影响 H318: 造成严重的眼睛损伤 H302+H312: 吞咽或皮肤接触有害。
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P301+P312+P330: 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口
WGK Germany:
3
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MSDS
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