BL-918

Dangerous Goods

CAS number：2101517-69-3 molecular formula：C23H15F8N3OS

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Information BL-918 BL-918 is a potent, orally active activator of UNC-51-like kinase 1 (ULK1) with EC50 of 24.14 nM and Kd of 0.719 μM. BL-918 induces cytoprotective autophagy for Parkinson's disease treatment. Targets ULK1 (Cell-free assay); ULK1 (Cell-free assay) 24.14 nM(EC50); 0.719 μM(Kd)

Specs

Chinese alias	-
English alias	MFCD31693829 \| (alphaR)-alpha-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(2,4-difluorophenyl)benzeneacetamide \| AKOS040759368 \| 7L84SG8RV6 \| BL 918 - Bio-X \| D81630 \| HY-124729 \| EN300-1725989 \| BL 918 \| EX-A3463 \| BDBWQANRZRCMMD-LJQAN
CAS number	2101517-69-3	molecular formula	C23H15F8N3OS
molecular weight	533.44 g/mol	Exact mass	10mM in DMSO
PSA	85.300 Å²	logp	6.100

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移