18:1 PA (1,2-二油酰-sn-丙三醇-3-磷酸盐(钠盐)): 可作为脂质体用于脂质体渗漏试验 可用于创建脂质体模板，以便合成磷酸钙(CaP)纳米壳 可用作脂质体/脂双层成分 作为神经元神经胶质培养基添加剂，用于研究星形胶质细胞磷脂酶D1 (PLD1)对于树枝状分支的作用 用于细胞色素c Trp59的化学发光试验 产品介绍： 18:1 PA (1,2-二油酰-sn-丙三醇-3-磷酸盐(钠盐))是阴离子脂质。 Phosphatidic Acid, Dioleoyl has been shown to activate PKC α, ε, or ζ isotypes in the cytosol of COS cells. This compound not only stimulates PKC-ζ-mediated phosphorylation of distinctive substrates, but additionally causes an upward shift in electrophoretic mobility of PKC &zeta. Furthermore, experiments have reported Phosphatidic Acid to be generated by hydrolysis of phosphatidylcholine, via phospholipase D (PLD). Mechanistic studies suggest activation of PLD by insulin and consequential generation of Phosphatidic Acid which then induces Raf-1 translocation to cell membranes. Raf-1 is an essential component to the mitogen-activated protein kinase cascade, and once it has crossed over to the plasma membrane, other factors may activate it through phosphorylation. An activator of multiple PKC isotypes Application 18:1 PA (1,2-dioleoyl-sn-glycerol-3-phosphate (sodium salt)): Can be used as liposomes for liposome leakage assays Can be used to create liposome templates for the synthesis of calcium phosphate (CaP) nanoshells Can be used as a liposome/lipid bilayer component As a neuronal glial culture medium additive to study the role of astrocyte phospholipase D1 (PLD1) on dendritic branching For chemiluminescent assays of cytochrome c Trp59
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1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt) (18:1 PA)
Dangerous GoodsCAS number：108392-02-5 molecular formula：C39H72O8PNa
overview
compound introduction
Specs
| Chinese alias | 1,2-二[顺式-9-十八碳烯酰基]-Sn-甘油-3-磷酸酯钠盐 | (Z)-(R)-3-(膦酰氧基)丙烷-1,2-二基二油酸酯单钠盐 | 二油酰磷脂酸(钠盐) | ||
| English alias | DOPA-NA | (Z)-(R)-3-(Phosphonooxy)propane-1,2-diyl dioleate sodium salt | L-α-Phosphatidic acid, dioleoyl sodium sal | 1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt | ||
| CAS number | 108392-02-5 | molecular formula | C39H72O8PNa |
| molecular weight | 722.95 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
Chloroform preparation solution of 1,2-dioleyl-sn-glyceryl-3-phosphate (sodium salt) | 2-dioleoyl-sn-glycero-3-phosphate (sodiumsalt), chloroform solution
