GSK256066

Dangerous Goods

CAS number：801312-28-7 molecular formula：C27H26N4O5S

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

GSK256066是PDE4B抑制剂，IC50为3.2 pM，与A-D各亚型亲和力相同，比对PDE1/2/3/5/6和PDE7的抑制性高380000倍和2500倍。A highly potent and selective inhibitor of phosphodiesterase 4 GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7 A highly potent and selective inhibitor of phosphodiesterase 4

Specs

Chinese alias	6-[[3-[(二甲基氨基)羰基]苯基]磺酰]-4-[(3-甲氧基苯基)氨基]-8-甲基-3-喹啉甲酰胺
English alias	DTXSID30230090 \| AC-32928 \| Histidine-Alanine dipeptide \| MFCD18206923 \| MLS006011116 \| 6-[3-(Dimethylcarbamoyl)phenyl]sulfonyl-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide \| SMR004702897 \| NCGC00346620-06 \| C27H26N4O5S \| NCGC00346620-08 \| SCHEMBL
CAS number	801312-28-7	molecular formula	C27H26N4O5S
molecular weight	518.58 g/mol	Exact mass	-
PSA	140.000 Å²	logp	3.800

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram：

GHS06 , GHS08 , GHS07

Signal word：

Danger

Hazard Statement：

H335: 可能引起呼吸道刺激 H373: 通过长时间或反复暴露对器官造成损害 H330: 吸入致命

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良，请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P320: 迫切需要特殊治疗（请参阅此标签上的...）。 P316: 立即寻求紧急医疗救助。 P319: 如果你