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GW0742

Dangerous Goods

CAS number:317318-84-6    molecular formula:C21H17F4NO3S2

overview

compound introduction

GW0742是一种有效的,选择性PPARβ/δ激动剂,IC50为1 nM,比作用于hPPARα和hPPARγ选择性高1000倍。 GW0742 是一种有效的 PPARβ 和 PPARδ 激动剂,在蛋白质结合实验中,对人 PPARδ 的 IC50 值为 1 nM;同时对人 PPARδ,PPARα 和 PPARγ 的 EC50 值分别为 1 nM,1.1 μM 和 2 μM GW0742

Specs

Chinese alias[4-[[[2-[3-氟-4-(三氟甲基)苯基]-4-甲基-5-噻唑基]甲基]硫代]-2-甲基苯氧基]乙酸
English aliasNCGC00092344-01 | BCP21281 | NSC-623957 | GW 610742 | SR-05000000447-2 | CHEBI:63055 | 2-(4-(((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methyl-5-thiazolyl)methyl)thio)-2-methylphenoxy)acetic acid | HMS3649P06 | A14958 | SW203822-2 | GW0 | PB47999 | s8020
CAS number317318-84-6molecular formulaC21H17F4NO3S2
molecular weight471.49 g/molExact mass-
PSA113.000 Ųlogp6.000

numbering system

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physicochemical properties

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Safety information

WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Production methods and uses

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upstream information

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downstream information

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MSDS

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