SB-297006 是一种 C-C chemokine receptor 3 (CCR3) 的拮抗剂,能够显著抑制 CCL11 处理的神经祖细胞的增殖和神经球形成,抑制抗原诱导的T(h)2和嗜酸性粒细胞在肺中的累积。SB-297006 可抑制CCL11诱导的Th2趋化性,其IC50值为2.5 μM。
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SB 297006
Dangerous GoodsCAS number:58816-69-6 molecular formula:C18H18N2O5
overview
compound introduction
Specs
| Chinese alias | N-苄基-4-硝基-L-苯丙氨酸乙酯 | ||
| English alias | N-Benzoyl-4-nitroaniline ethyl ester | Ethyl (2S)-2-benzamido-3-(4-nitrophenyl)propanoate | AC-36264 | SB 297006 | AS-56057 | B6053 | BDBM50100041 | MFCD19690954 | HY-103361 | (S)-Ethyl 2-benzamido-3-(4-nitrophenyl)propanoate | EX-A2738 | (S)-2-Benzoylami | ||
| CAS number | 58816-69-6 | molecular formula | C18H18N2O5 |
| molecular weight | 342.35 g/mol | Exact mass | 10mM in DMSO |
| PSA | 101.000 Ų | logp | 3.300 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram:
GHS09 , GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害 H400: 对水生生物有剧毒
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P301+P317: 如果被吞咽:请寻求医疗帮助。
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MSDS
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