Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

Dangerous Goods

CAS number：2245697-85-0 molecular formula：C25H34N4O10.HCl

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。可用于合成 PROTAC 分子。 Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs。

Specs

Chinese alias	N-(14-氨基-3,6,9,12-四氧杂酸酯-1-基)-2-[[2-(2,6-二氧代-3-哌啶基)-2,3-二氢-1,3-二氧-1H-异吲哚-4-基]氧基]乙酰胺盐酸盐 \| 沙利度胺-O-酰胺基-PEG4-C2-NH2 盐酸盐
English alias	Thalidomide - linker 2 \| N-(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
CAS number	2245697-85-0	molecular formula	C25H34N4O10.HCl
molecular weight	587.02 g/mol	Exact mass	≥95%(HPLC)
PSA	185.000 Å²	logp	-

numbering system

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physicochemical properties

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Safety information

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P301+P312: 如误吞咽：如感觉不适，呼叫急救中心/医生。