compound introduction
Tiplaxtinin是一种有效的，具有选择性的纤溶酶原激活物抑制剂-1 (PAI-1) 抑制剂的原料，IC50 为 2.7 μM
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Tiplaxtinin
Dangerous GoodsCAS number：393105-53-8 molecular formula：C24H16F3NO4
overview
Specs
| Chinese alias | α-氧代-1-(苯基甲基)-5-[4-(三氟甲氧基)苯基] -1H-吲哚-3-乙酸 | 替普沙汀 | (1-苄基-5-(4-(三氟甲氧基)苯基)-1H-吲哚-3-基)氧乙酸 | 替普拉汀 | ||
| English alias | PAI-039 | WAY-168039 | 2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxoacetic acid | FT-0700303 | HY-15253 | Tiplasinin [USAN:INN] | A14190 | Tiplasinin (USAN) | 2-[1-benzyl-5-[4-(triluoromethoxy)phenyl]indol-3-yl]-2-oxoacetic acid | CHEBI:1777 | ||
| CAS number | 393105-53-8 | molecular formula | C24H16F3NO4 |
| molecular weight | 439.38 g/mol | Exact mass | 10mM in DMSO |
| PSA | 68.500 Ų | logp | 5.800 |
numbering system
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physicochemical properties
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Safety information
Hazard Statement：
H413: 可能对水生生物造成长期的有害影响
Statement of Preventive Measures：
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。
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MSDS
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