URB937 是口服有效的、外周限制的 FAAH 抑制剂,IC50 值为 26.8 nM,可增加 anandamide 水平。URB937 不能影响脑内 FAAH 水平 (无法透过血脑屏障) Product description URB937 is an orally active and peripherally restricted FAAH inhibitor (IC50=26.8 nM) and increases anandamide levels. URB937 fails to affect FAAH activity in the brain (not penetrate the blood-brain barrier).
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URB 937
Dangerous GoodsCAS number:1357160-72-5 molecular formula:C20H22N2O4
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| Chinese alias | 3'-氨基甲酰基-6-羟基-[1,1'-联苯]-3-基 环己基氨基甲酸酯 | ||
| English alias | cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester | DTXSID801018151 | BDBM50437227 | MS-25529 | [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate | 3'-(Aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl N-cyclohexylcarbamate | AC-365 | ||
| CAS number | 1357160-72-5 | molecular formula | C20H22N2O4 |
| molecular weight | 354.4 g/mol | Exact mass | - |
| PSA | 102.000 Ų | logp | 3.500 |
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