内源性大麻素受体混合拮抗剂/激动剂的周边浓度高于anandamide。GPR55和CB2的完全激动剂和CB1的部分拮抗剂/激动剂(GPR55,CB2和CB1受体的EC | 50 |值分别为12、381和2920 nM)。在体内诱导体温过低。 Endogenous cannabinoid receptor mixed antagonist/agonist found in higher concentrations peripherally than anandamide. Full agonist at GPR55 and CB2 and partial antagonist/agonist at CB1 (EC|50|values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively). Induces hypothermia in vivo.
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Virodhamine
CAS number:287937-12-6 molecular formula:C22H37NO2
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compound introduction
Specs
| Chinese alias | 维罗达明 | ||
| English alias | (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid 2-amino-ethyl ester | 5,8,11,14-Eicosatetraenoic acid, 2-aminoethyl ester, (5Z,8Z,11Z,14Z)- | (2-Aminoethyl) 5Z,8Z,11Z,14Z-eicosatetraen ester | BDBM50171285 | O-arachidonoyl ethanolamine | Arachidonic Acid- | ||
| CAS number | 287937-12-6 | molecular formula | C22H37NO2 |
| molecular weight | 347.53 g/mol | Exact mass | - |
| PSA | 52.300 Ų | logp | 5.700 |
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RTECS:
KQ6300000
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