compound introduction
胆碱非诺贝特是非诺贝特酸的胆碱盐，用于降低低密度脂蛋白和极低密度脂蛋白，同时增加高密度脂蛋白。非诺贝特酸的结构包含羧酸部分而不是酯部分，这在形成稀有酸与酮的氢键型堆积相互作用中起着重要作用。另外，非诺贝特酸中缺少异丙基会使羧基与酮羰基对齐，这有利于在分子识别中区分酸和非诺贝特。 Choline Fenofibrate is a choline salt of fenofibric acid used to lower low-density lipoproteins and very low-density lipoproteins while increasing high density lipoproteins. The structure of fenofibric acid contains a carboxylic acid moiety instead of an ester moiety which is an important role in the formation of a rare acid to ketone hydrogen-bond-type packing interaction. In addition, the lack of an isopropyl group in fenofibric acid aligns the carboxyl group with the ketone carbonyl group which is beneficial for distinguishing between the acid and fenofibrate in molecular recognition.
