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TM5441

Dangerous Goods

CAS number：1190221-43-2    molecular formula：C21H17ClN2O6

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overview

compound introduction

Information TM5441 TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 ranging between 9.7 μM and 60.3 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines. Targets PAI-1 (Cell-free assay) 9.7 μM

Specs

Chinese alias-
English aliasBenzoic acid,5-​chloro-​2-​[[2-​[2-​[[3-​(3-​furanyl)​phenyl]​amino]​-​2-​oxoethoxy]​acetyl]​amino]​-
CAS number1190221-43-2molecular formulaC21H17ClN2O6
molecular weight428.82 g/molExact mass10mM in DMSO
PSA118.000 Ųlogp2.239

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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