Darapladib

Dangerous Goods

CAS number：356057-34-6 molecular formula：C36H38F4N4O2S

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Darapladib (SB-480848)是不可逆的lipoprotein-associated phospholipase A2 (Lp-PLA2)抑制剂，其IC50为0.25 nM。 Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM.

Specs

Chinese alias	-
English alias	BCP9000585 \| BDBM50524488 \| DARAPLADIB [MI] \| SB 480848;N-[2-(diethylamino)ethyl]-2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1H-Cyclopentapyrimidine-1-acetamide \| SB 480848 \| NCGC00386337
CAS number	356057-34-6	molecular formula	C36H38F4N4O2S
molecular weight	666.77 g/mol	Exact mass	-
PSA	81.500 Å²	logp	7

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS09 , GHS05

Signal word：

Danger

Hazard Statement：

H318: 造成严重的眼睛损伤 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响

Statement of Preventive Measures：

P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。 P391: 收集溢出物 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。