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JG98

Dangerous Goods

CAS number：1456551-16-8    molecular formula：C24H21Cl2N3OS3

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overview

compound introduction

JG-98 是 Hsp70 的变构抑制剂，它与Hsp70家族成员保守的深袋紧密结合。JG-98 可诱导经典的凋亡特征，包括与程序性细胞死亡和膜联蛋白染色阳性相符的形态变化。JG-98 具有抗癌的活性。 Information JG98 JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity. Targets Hsp70

Specs

Chinese alias-
English aliasThiazolium,2-​[(Z)​-​[(5E)​-​5-​(6-​chloro-​3-​methyl-​2(3H)​-​benzothiazolylidene)​-​3-​ethyl-​4-​oxo-​2-​thiazolidinylidene]​methyl]​-​3-​(phenylmethyl)​-​,chloride (1:1)
CAS number1456551-16-8molecular formulaC24H21Cl2N3OS3
molecular weight534.54 g/molExact mass≥99%
PSA106.000 Ųlogp3.928

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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