compound introduction
产品介绍： 13-氧化ODE由大鼠结肠粘膜中存在的NAD +依赖性脱氢酶从13-HODE产生。1直肠内滴注大鼠时，可刺激细胞增殖。2在兔网状细胞血浆和线粒体膜的制剂中也已检测到，大多数被酯化为磷脂。通过13-LO的活性，推测13-oxoODE的产生与网状细胞向红细胞的成熟有关。13-OxoODE是PPARα（过氧化物酶体增殖物激活受体α）的激活剂。 Product description： 13-OxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa.1 Stimulates cell proliferation when instilled intrarectally in rats.2 Has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes through the activity of 15-LO. 13-OxoODE is an activator of PPAR α(peroxisome proliferator-activated receptor α).
