Substance P TFA

Dangerous Goods

CAS number：148470-19-3 molecular formula：C63H98N18O13S

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor ( NK1-receptor , NK1R ) In Vitro The neuropeptide substance P (SP) that are mediated by the neurokinin 1 receptor (NK1-R) desensitize and resensitize, which may be associated with NK1-R endocytosis and recycling. SP and the NK1-R are internalized into the same clathrin immunoreactive vesicles, and then sorted into different compartments. SP is intact at the cell surface and in early endosomes, but slowly degraded in perinuclear vesicles. SP induces clathrin-dependent internalization of the NK1-R. The SP/NK1-R complex dissociates in acidified endosomes. SP is degraded, whereas the NK1-R recycles to the cell surface. SP induces internalization of the NK1-R both in transfected epithelial cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:NK1 Human Endogenous Metabolite

Specs

Chinese alias	-
English alias	AS-77493 \| Substance p (1-11) \| Substanz-P \| [125I]SP (human, mouse, rat) \| [3H]-SP \| Neurokinin P TFA \| BDBM50001450 \| Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2.(Substance P) \| CCRIS 7229 \| Neurokinin-1 \| Neurokinin PNeurokinin P \| Arg-Pro-Lys-Pro-
CAS number	148470-19-3	molecular formula	C63H98N18O13S
molecular weight	1347.6 g/mol	Exact mass	≥99%
PSA	544.000 Å²	logp	-2.300

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用