product description： (2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone is a chiral imidazolidinone organocatalyst, developed by MacMillan and co-workers. application： (2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone is a second-generation MacMillan catalyst, which can be used as a chiral organocatalyst in: The chiral transformation reaction, including Friedel-Crafts and Mukaiyama-Michael reactions. The preparation of substituted spiroundecenetriones via asymmetric domino Knoevenagel/Diels-Alder reactions. The asymmetric synthesis of β-hydroxy aldehydes and their dimethylacetals via aldehyde-aldehyde aldol condensation reaction. The enantioselective α-fluorination of aldehydes using N-fluorobenzenesulfonamide as a fluorinating agent. The stereoselective preparation of (oxomethyl)oxabicyclo[3.2.1]octenones and tricyclic pyrroles via [4+3] cycloaddition of (trialkylsiloxy)pentadienals to furans. Metal-free OrganoCatalyst technology for asymmetric catalysis. Catalyzes asymmetric indole alkylations, Friedel-Crafts alkylations, and a broad range of conjugate addition reactions in high enantiomeric excess.
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(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
Dangerous GoodsCAS number：346440-54-8 molecular formula：C15H22N2O
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| Chinese alias | (2S,5S)-(-)-5-苯甲基-2-叔丁基-3-甲基-4-咪唑烷酮 | (2S,5S)-5-苄基-2-叔丁基-3-甲基-4-咪唑烷酮 | (2S,5S)-2-叔丁基-3-甲基-5-苯甲基-4-咪唑烷酮 | (2S,5S)-(-)-2-叔丁基-3-甲基-5-苄基-4-咪唑烷酮 | ||
| English alias | Q27270710 | (2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone | T70804 | (2S,5S)-(-)-5-Benzyl-2-tert-butyl-3-methyl-4-imidazolidinone | J-019688 | AKOS000272101 | NSC 400336 | Macmillan's imidazolidinone catalysts second generation catalyst [MI | ||
| CAS number | 346440-54-8 | molecular formula | C15H22N2O |
| molecular weight | 246.35 g/mol | Exact mass | ≥97%(GC) |
| PSA | 32.299 Ų | logp | 3.000 |
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WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
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MSDS
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346440-54-8 | (2S,5S)-(−)-2-tert-Butyl-3-methyl-5-benzyl-4-imidaz olidinone.pdf
