Oligomycin is a macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. The compound is a mixture of isomers A ,B , and C .Cancer cell studies show that Oligomycin does not activate the hypoxia-induced factor, however, it enhances the bioenergetic adaptation of heterogeneous bioenergetically organized cells. Oligomycin has been shown to decreased the cyclin D1 protein expression levels Oligomycin is a macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. The compound is a mixture of isomers A ,B , and C .Cancer cell studies show that Oligomycin does not activate the hypoxia-induced factor, however, it enhances the bioenergetic adaptation of heterogeneous bioenergetically organized cells. Oligomycin has been shown to decreased the cyclin D1 protein expression levels A specific inhibitor of the mitochondrial ATP-synthase.
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Oligomycin
Dangerous GoodsCAS number：1404-19-9 molecular formula：C45H74O11
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Oligomycin a, b, c mixture | Oligomycin Complex | ||
| CAS number | 1404-19-9 | molecular formula | C45H74O11 |
| molecular weight | 791.07(for Oligomyci | Exact mass | - |
| PSA | 180.000 Ų | logp | 7.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06 , GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒 H302: 吞食有害 H370: 对器官造成损害
Statement of Preventive Measures：
P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P308+P316: 如果暴露或担心：立即寻求紧急医疗救助。
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US),Eyeshields,Faceshields,Gloves
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