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Salubrinal

Dangerous Goods

CAS number:405060-95-9    molecular formula:C21H17Cl3N4OS

overview

compound introduction

Salubrinal是一种选择性的eIF2α 脱磷酸作用抑制剂,可以抑制ER应激介导的细胞凋亡,EC50约为15 μM。A selective inhibitor of eIF-2α used to study ER stress-induced apoptosis Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM. A selective inhibitor of eIF-2α used to study ER stress-induced apoptosis

Specs

Chinese alias沙鲁胺 | (2E)-3-苯基-N- [2,2,2-三氯-1 - [[(8-喹啉基氨基)硫代甲基]氨基]乙基] -2-丙烯酰胺
English aliasAC-33176 | (2E)-3-phenyl-N-{2,2,2-trichloro-1-[(quinolin-8-ylcarbamothioyl)amino]ethyl}prop-2-enamide | F0095-1218 | AKOS016042385 | CHEBI:91873 | SCHEMBL6477826 | 2-Propenamide, 3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]
CAS number405060-95-9molecular formulaC21H17Cl3N4OS
molecular weight479.81 g/molExact mass≥98%
PSA98.100 Ųlogp5.200

numbering system

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physicochemical properties

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Safety information

pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移
WGK Germany:
3

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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