Tofacitinib (CP-690550) Citrate

Dangerous Goods

CAS number：540737-29-9 molecular formula：C16H20N6O.C6H8O7

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Tofacitinib (CP-690550) Citrate是一种新型JAK3抑制剂，IC50为1 nM，作用于JAK2和JAK1选择性比其低20到100倍。A selective JAK3 inhibitor Tofacitinib (CP-690550) Citrate is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1. A selective JAK3 inhibitor

Specs

Chinese alias	枸橼酸托法替尼
English alias	D09783 \| Xeljanz \| 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate \| CP-690550 Citrate (Tofacitinib Citrate) \| UNII-O1FF4DIV0D \| 3-((3R,4R)-4-Methyl-3-(methyl(7H
CAS number	540737-29-9	molecular formula	C16H20N6O.C6H8O7
molecular weight	504.49 g/mol	Exact mass	≥99%
PSA	221.000 Å²	logp	-

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS08 , GHS07

Signal word：

Danger

Hazard Statement：

H302: 吞食有害 H360: 可能损害生育力或未出生的孩子

Statement of Preventive Measures：

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。

WGK Germany：