CAS number：332382-54-4 molecular formula：C22H22N2O3
ML-SA1 作为一种选择性 TRPML 激动剂，通过促进溶酶体的酸化和蛋白酶活性，抑制登格病毒 2 (DENV2) 和寨卡病毒 (ZIKV)。ML-SA1 抗 DENV2 RNA 和 ZIKV RNA 的 IC50 值分别为 8.3 μM 和 52.99 μM。ML-SA1 诱发自噬。ML-SA1可用于广谱抗病毒研究。 Application ML-SA1 has been used as a transient receptor potential cation channel mucolipin 1 (TRPML1/ML1) agonist.
| Chinese alias | - | ||
| English alias | 332382-54-4 | ML SA1 | ML-SA1 | 2-[2-oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione | 2-(2-oxo-2-(2,2,4-Trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl)isoindoline-1,3-dione | 2-[2-oxo-2-(2,2,4-trimethyl-3,4-dihydroquin | ||
| CAS number | 332382-54-4 | molecular formula | C22H22N2O3 |
| molecular weight | 362.42 g/mol | Exact mass | - |
| PSA | 57.700 Ų | logp | 3.300 |
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