圆弧偶氮酸（CPA）是由多种 曲霉 和 青霉菌 种合成的tetramic酸。 应用 圆弧青霉菌来源圆弧偶氮酸用于： 作为标准品，用于薄层色谱法（TLC）检测和定量黄曲霉毒素。 作为培养基成分，用于不含Ca2+的DMEM（含10％胎牛血清（FBS））。 作为肌质网/内质网Ca2+ -ATP酶的可逆抑制剂，检测腔内钙在内质网（ER）-至-高尔基体转运过程中的作用。 作为内质网Ca2+-ATP酶的阻滞剂，处理神经元；研究内质网（ER）在Ca2+诱导的Ca2+ 释放（CICR）抑制 SERCA 过程中，对释放和维持Ca2+ 的影响。 Cyclopiazonic acid (CPA), a tetramic acid is synthesized by various Aspergillus and Penicillium species. Product Application Cyclopiazonic acid from Penicillium cyclopium has been used: as a standard in aflatoxin detection and quantification by thin layer chromatography (TLC) as a component in Ca2+-free DMEM/10% fetal bovine serum (FBS) as a reversible inhibitor of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) to examine the role of luminal calcium in endoplasmic recticulum (ER)-to-Golgi trafficking as an endoplasmic reticulum Ca2+-ATPase blocker, to treat neurons and also to study the role of the endoplasmic reticulum (ER) in releasing and sustaining Ca2+ during Ca2+-induced Ca2+ release (CICR) to inhibit SERCA
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Cyclopiazonic acid from Penicillium grisefulvum
Dangerous GoodsCAS number：18172-33-3 molecular formula：C20H20N2O3
overview
compound introduction
Specs
| Chinese alias | 环匹阿尼酸,环二氮酸 | ||
| English alias | NSC 117181，(6aS,11aR,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-6a,7,11a,11b-tetrahydro-2H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9(6H)-one， | ||
| CAS number | 18172-33-3 | molecular formula | C20H20N2O3 |
| molecular weight | 336.38 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06
Signal word：
Danger
Hazard Statement：
H300: 吞咽致命
Statement of Preventive Measures：
P301+P310: 如误吞咽：立即呼叫急救中心/医生。 P264: 处理后要彻底洗手。
WGK Germany：
3
Personal protective equipment：
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS：
UY8587000
Production methods and uses
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downstream information
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MSDS
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