compound introduction
Isavuconazole是一种广谱的三唑类药物，具有抗多种真菌病原体的活性。板蓝康唑对皮肤芽生菌和荚膜组织胞浆菌等二形性真致病真菌具有活性，对皮肤真菌也具有活性。Isavuconazole对FLC耐药的念珠菌属、曲霉属和不常见的机会真菌具有广谱抗真菌活性。 Isavuconazole is an extended-spectrum triazole with activity against a wide variety of fungal pathogens. Isavuconazole has shown activity against the dimorphic true pathogenic fungi, such as|Blastomyces dermatitidis|and|Histoplasma capsulatum|, and is also active against uncommon dematiaceous fungi such as|Exophiala spp.|and|Phialophora spp.|as well as against dermatophytic species. Isavuconazole showed broad spectrum antifungal activity against FLC-resistant strains of|Candida spp.|,|Aspergillus spp.|and uncommon opportunistic fungal species.
