CAS number：303-81-1 molecular formula：C31H36N2O11
新生霉素是一种氨基香豆素抗生素，从多种链霉菌中分离出来。新霉素具有广谱革兰氏阳性活性，已在临床上使用。新生霉素是Topo IIα（细菌DNA促旋酶）的有效抑制剂，并充当GyrB催化的ATPase反应的竞争性抑制剂。 Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive activity and was used clinically. Novobiocin is a potent inhibitor of Topo II α (bacterial DNA gyrase) and acts as a competitive inhibitor of the ATPase reaction catalysed by GyrB.
| Chinese alias | - | ||
| English alias | KBio2_004970 | Novobiocin, Antibiotic for Culture Media Use Only | Novobiocina [INN-Spanish] | 17EC19951N | 4urn | DTXSID3041083 | KBio3_002881 | Novobiocine (INN-French) | Spectrum4_000457 | (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbu | ||
| CAS number | 303-81-1 | molecular formula | C31H36N2O11 |
| molecular weight | 612.62 g/mol | Exact mass | - |
| PSA | 196.000 Ų | logp | 3.300 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
