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DDD107498

Dangerous Goods

CAS number：1469439-69-7    molecular formula：C27H31FN4O2

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numbering system
physicochemical properties
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overview

compound introduction

DDD107498是一种新型有效的多级抗疟疾制剂，可在疟原虫生命周期的多个阶段发挥作用； DDD107498具有可接受的安全性和良好的药代动力学特征。翻译延伸因子2（eEF2）被发现是DDD107498的分子靶标。因子eEF2负责GTP依赖的核糖体沿着信使RNA易位，对蛋白合成十分重要 Information DDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.

Specs

Chinese alias-
English aliasNCGC00490685-01 | DDD498 | E3OC1CU1F4 | 6-Fluoro-2-(4-(4-morpholinylmethyl)phenyl)-N-(2-(1-pyrrolidinyl)ethyl)-4-quinolinecarboxamide | BDBM50550147 | AC-35743 | BCP31981 | BENUHBSJOJMZEE-UHFFFAOYSA-N | 6-fluoro-2-[4-(morpholin-4-ylmethyl)phenyl]-N-(2-pyr
CAS number1469439-69-7molecular formulaC27H31FN4O2
molecular weight462.56 g/molExact mass-
PSA57.700 Ųlogp3.200

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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MSDS

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