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LY364947

Dangerous Goods

CAS number：396129-53-6    molecular formula：C17H12N4

overview
Specs
numbering system
physicochemical properties
Safety information
Production methods and uses
Related
MSDS
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overview

compound introduction

LY364947是一种有效的，ATP竞争性的TGFβR-I抑制剂，IC50为59 nM，比作用于TGFβR-II选择性高7倍。 LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, shows 7-fold selectivity over TGFβR-II. A selective ATP-competitive inhibitor of TGF-β Receptor I kinase.

Specs

Chinese alias-
English aliasSB19489 | 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE | s2805 | HMS3229M09 | PY1 | 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]quinoline | 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline | Q-102724 | SCHEMBL21233972 | PS-7269 | BCP9000886 | GTPL6050 | LY364947 | LY-
CAS number396129-53-6molecular formulaC17H12N4
molecular weight272.3 g/molExact mass-
PSA54.500 Ųlogp2.700

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：
GHS06 , GHS09
Signal word：
Danger
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H301: 吞咽会中毒 H400: 对水生生物有剧毒
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P301+P310: 如误吞咽：立即呼叫急救中心/医生。
WGK Germany：
3
Personal protective equipment：
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Production methods and uses

No production method and use information yet

Related

upstream information

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downstream information

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MSDS

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