compound introduction
SD-208是口服活性的ATP竞争性TGF-βRI抑制剂，IC50为49 nM，比对TGF-βRII和其它激酶的抑制性高100倍和17倍。A TGF-β signaling blocker SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, >100-fold selectivity over TGF-βRII. A TGF-β signaling blocker
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SD-208
Dangerous GoodsCAS number：627536-09-8 molecular formula：C17H10ClFN6
overview
Specs
| Chinese alias | - | ||
| English alias | 2-(5-chloro-2-fluorophenyl)-4-(4-pyridylamino)pteridine | BCP02214 | FT-0700345 | HMS3604B06 | 1608481-61-3 | 2-(5-Chloro-2-fluorophenyl)-4-[(4-pyridyl)amino]pteridine | AKOS024457517 | NCGC00165898-01 | A833974 | WLN: 1U2R BQ CO1 | s7624 | SCHEMBL411646 | ||
| CAS number | 627536-09-8 | molecular formula | C17H10ClFN6 |
| molecular weight | 352.75 g/mol | Exact mass | - |
| PSA | 76.500 Ų | logp | 3.000 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害
Statement of Preventive Measures：
P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P301+P317: 如果被吞咽：请寻求医疗帮助。
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Gloves
Production methods and uses
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upstream information
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downstream information
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MSDS
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