compound introduction
Volasertib(BI6727)是高活性PLK1抑制剂，IC50为0.87 nM，比对Plk2和Plk3的抑制性高6倍和65倍。 Volasertib(BI6727) is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM; shows 6- and 65-fold greater selectivity against Plk2 and Plk3.
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Volasertib (BI 6727)
Dangerous GoodsCAS number：755038-65-4 molecular formula：C34H50N8O3
overview
Specs
| Chinese alias | - | ||
| English alias | BCPP000341 | DTXSID901025694 | Benzamide, N-(trans-4-(4-(cyclopropylmethyl)-1-piperazinyl)cyclohexyl)-4-(((7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl)amino)-3-methoxy- | BDBM50402023 | MLS006011195 | n-[trans-4-[4-(cyclop | ||
| CAS number | 755038-65-4 | molecular formula | C34H50N8O3 |
| molecular weight | 618.83 g/mol | Exact mass | - |
| PSA | 106.000 Ų | logp | 4.600 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06 , GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H373: 通过长时间或反复暴露对器官造成损害 H300: 吞咽致命 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P362+P364: 脱掉沾污的
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
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