CAS number：338404-52-7 molecular formula：C19H12Cl3N3OS
CITCO 是一种组成型雄甾烷 (Constitutive androstane) 受体激动剂，抑制脑肿瘤干细胞 (BTSCs) 的生长和扩增。CITCO 是一种咪唑并噻唑衍生物，其作为人 CAR 的选择性激动剂起作用。CITCO 对于孕烷 X 受体 (PXR) 的 EC50 为 49 nM，并且对其他核受体没有活性。 Product Describtion: CITCO is an imidazothiazole derivative. It stimulates human constitutive androstane receptor (CAR) nuclear translocation. Product Application： CITCO has been used for the activation of mouse constitutive androstane receptor (CAR) and human CAR.
| Chinese alias | 6-(4-氯苯基)咪唑并[2,1-b] [1,3]噻唑-5-甲醛-O-(3,4-二氯苄基)肟 | ||
| English alias | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime | SR-05000000441-2 | YSZC2161 | HMS3403D09 | 6-(4-Chlorophenyl)-imidazo(2,1-b)thiazole-5-carboxaldehyde O-((3,4-dichlorophenyl)methyl)oxime | 6-(4-CHLOROPHENYL)IMIDAZO[2, | ||
| CAS number | 338404-52-7 | molecular formula | C19H12Cl3N3OS |
| molecular weight | 436.74 g/mol | Exact mass | - |
| PSA | 67.100 Ų | logp | 7.300 |
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