NU7026是一种有效的DNA-PK抑制剂,IC50为0.23 μM,作用于DNA-PK比作用于PI3K选择性高60倍,抑制ATM和ATR活性。An antiproliferative agent, and inhibitor of DNA-PK. NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM, 60-fold selective for DNA-PK than PI3K and inactive against both ATM and ATR. An antiproliferative agent, and inhibitor of DNA-PK.
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NU7026
Dangerous GoodsCAS number:154447-35-5 molecular formula:C17H15NO3
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 2-(Morpholin-4-yl)-benzo[h]chromen-4-one | 2-(morpholin-4-yl)benzo[h]chromen-4-one | CCG-206743 | HMS3675M22 | EC-000.2421 | NU 7026 | BCP04736 | BDBM50098126 | HSCI1_000223 | BCP29553 | NU-7026 | 2-MORPHOLINO-4H-BENZO(H)CHROMEN-4-ONE | AKOS015994580 | 2- | ||
| CAS number | 154447-35-5 | molecular formula | C17H15NO3 |
| molecular weight | 281.31 g/mol | Exact mass | - |
| PSA | 38.800 Ų | logp | 2.800 |
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physicochemical properties
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Safety information
WGK Germany:
3
Personal protective equipment:
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Production methods and uses
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