CAS number：856925-71-8 molecular formula：C18H16N2O2
(-)-Blebbistatin是布雷他汀的S对映体。 Blebbistatin是有效且选择性的 myosin II 抑制剂，IC50 范围为0.5至5 μM。(-)-布雷他汀已被用于研究对心肌收缩力的影响以及凝血酶对肌动球蛋白收缩性的影响。 (-)-Blebbistatin is an S enantiomer of blebbistatin. Blebbistatin is a potent and selective myosin II inhibitor with IC50s ranging from 0.5 to 5 μM.
| Chinese alias | ()-II型肌球蛋白 | (−)-II型肌球蛋白 | 1-苯基-1,2,3,4-四氢-4-羟基[2,3-B]-7-甲基喹啉-4-酮 | ||
| English alias | 8WII7624I5 | (-)Blebbistatin | (S)-blebbistatin | (S)-3a-hydroxy-6-methyl-1-phenyl-3,3a-dihydro-1H-pyrrolo[2,3-b]quinolin-4(2H)-one | (S)-(-)-Blebbistatin | Blebbistatin (S)-form [MI] | 1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2.3-b]-7-methylquinolin- | ||
| CAS number | 856925-71-8 | molecular formula | C18H16N2O2 |
| molecular weight | 292.33 g/mol | Exact mass | ≥98% |
| PSA | 52.900 Ų | logp | 2.400 |
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